Category Archives: Physiology

The Exercise Myth – Strength and Activity

From Chris Highcock’s wonderful short PDF book which you can buy here. Chris’s book opens with the best context for Fitness and its link to health and how we grow old that I have yet seen. This site has talked … Continue reading

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“Cancering” – It’s all about systems not one thing

An exceptional piece that sheds light on the systemic issues related to Cancer. As Michael points out in the 55 is the flaw in how we approach science – reductionism – this video shows how different medicine will be. Dr … Continue reading

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Ancestry Foundation – A great centre of information – Videos from the conference

Earlier this month, the Ancestry Foundation hosted the first of what will be many conferences on Health as seen through the perspective of Evolution. Here is the link to the many excellent videos Here is the link to the slides and here … Continue reading

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So when will you lose your health? – Part 3 – When you don’t know this

Every day we read of a new study that says “This is bad for you” and “This is good for you”. No wonder when it comes to taking control of our health, we are confused by science. I read a … Continue reading

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So when will you lose your health – Part 2 – When you live in the wrong environment

You get ill when you look like this – this is how I looked aged 59 – I weighed 205 lbs. How I look here has all the signs that you have not lived your life according to the rules. … Continue reading

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Why are we so fat in rural settings? – Part 3 – Our Ancestry!

Prince Edward Island, where I live, has a very high obesity rate. So do many rural parts of America and of cource the rest of Atlantic Canada. We have looked at why there is an physical environmental difference between cities and … Continue reading

Posted in "Paleo", A New Vision, Aging, Ancestry, Constraints, Context, Diet, Environments, Evolutionary Novelty, Physiology, Plateau, Population, The Plateau, The Science, Theses | Tagged , , | 4 Comments

Your Mind and your Health – Part 2 – The Power of Neuroplasticity

This is the conventional picture of the brain – a thing with discrete compartments – a thinking machine. This idea of the brain – which is also how most of us “see” the body and so organize medicine is wrong. … Continue reading

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Your Mind & Your Health – Part 1 – Overcoming bad environments

Most of us understand that if we eat better (whatever better means) and if we are more active, our health will improve. But few of us know that if we use our mind “better” that this too will help us … Continue reading

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Diet – Where your ancestral heritage is important

Surely we must have adapted to agriculture by now? The answer is no and sort of yes to that question. It depends on what your ancestral heritage is or how long you have been exposed to agriculture. Let’s take dairy. … Continue reading

Posted in Ancestry, Constraints, Context, Diet, Environments, Evolutionary Novelty, Forces of Natural Selection, Physiology, Population, The Science, Theses | 12 Comments

Where can we find answers to the questions raised by Michael Rose? A Hack Community

Finding out how best to live in a way more attuned to our Paleo past is not a well established protocol yet. How do we give up sugar if we are addicted? What is the best form of activity to … Continue reading

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The PaleoGraphic – The Story in Pictures

Learn more about the Paleo Diet. From Paleolithicdiet.com

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Michael’s Recent Interview

Michael is interviewed by Jimmie Moore on how Evolution plays such a role and also on how diet is so important. Here MR summarizes the key factors of the 55 in a few minutes.  

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Talking about Environments – carbs are novel

This is what most of us – especially our Dr’s think is the ideal start to the day. A cup of oatmeal is 60 grams of carbs. The National Academy of Sciences recommends no less than 120 grams of carbs … Continue reading

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Talking about environments – What’s in your shampoo, soap, deodorant and face cream?

I am just waking up to Michael’s warning about novel environments – here is the lowdown on what goes on in our bathrooms! If you want to know more go here. It scares me to think of how I could … Continue reading

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Talking about Environments – What about your mouth?

Ideally our mouths should be on the alkaline side. Before the modern diet, they were. Before the modern diet there was next to no caries. Today we brush our teeth to give us a chance of beating caries. But what … Continue reading

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As primates we need to live in the “right” social environment – much of our illness stems from a poor fit – the cure is a better fit.

A central tenet of Michael’s is that we do best in environments that fit our evolved state. Diet is a very important aspect of finding the best fit. But so is our social environment. Practical work at one of Canada’s … Continue reading

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Michael’s Rose’s “Twin Sister?” – Dr Mary Vernon – The practical aspect of the 55 Theses

No one I have found so far explains how our metabolism works better than Dr Vernon – a GP who could not help any of her diabetic patients get well by following the “rules”. Who then became an expert in … Continue reading

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The most important social environment to get right – the family

Michael Rose is clear – the closer we can live in environments that we have evolved to thrive in, the better off we will be. No environment has more of an effect on our well being than our family. For … Continue reading

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Sir Michael Marmot to expand the Whitehall Study to look at why we “age” differently

Marmot’s Whitehall Study is a longitudinal study that has studied the effects of social status on health. He used as his sample a large number of well educated British Civil Servants – Hence “Whitehall”. A key finding has been the … Continue reading

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Cancer is not a disease but a part of mammalian life – Paul Davies

In Thesis 15 Michael makes the point that cancer is not a disease but is part of how we as a mammal evolve. Here Paul Davies backs him up. The video is here We can prevent it

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Thesis # 3

Thesis #3. Health and adaptation thus reflect the action of natural selection on a population in its previous environments, not its present environment, when these differ. For the purpose of re-founding medicine scientifically, theses 2 and 3 direct us to … Continue reading

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Thesis 25

Thesis #25 – Repairing all forms of cumulative damage and altering all types of regulatory signaling during the aging phase will also fail to fully alleviate aging, because some features of aging will arise from the absence of structural gene-products … Continue reading

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Thesis 30

Thesis #30 – The forces of natural selection plateau at zero values at very late adult ages, and do not decline further for all subsequent ages. This is the most important thing of all, even if no one understood what … Continue reading

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Thesis 33

Thesis #33 – When late-adult plateaus in survival and reproduction occur, members of biological cohorts that reach such plateaus will show stabilization of some but not necessarily all functional characters. Evolutionary theory makes a simple prediction about how the key … Continue reading

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Thesis 34

Thesis #35 – Severe antagonistic pleiotropy can cause the evolution of zero late-adult survival probability even under ideal conditions, when genetic trade-offs between early reproduction and subsequent adult survival are sufficiently strong. Not all organisms have three phases to their … Continue reading

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Thesis 36

Thesis #36 – Experimental populations which have evolved different time-points for the cessation of aging can be used to uncover the biological foundations that determine the timing of the cessation of aging. During the 1980s and 1990s, my laboratory devoted … Continue reading

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Thesis 38

Thesis #38 – Some environmentally-induced variation in patterns of aging reflects the impact of selectively-favored patterns of life-history plasticity, but some environmental variation in aging does not reflect adaptive plasticity, such as that due to novel environments. An important distinction … Continue reading

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Thesis 41

Thesis #41 – Experimental strategies for the study of aging that involve the use of environments that are evolutionarily novel will systematically impair the scientific study of aging, as natural selection will not have previously fostered adaptation to such novel … Continue reading

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Thesis 47

Thesis #47 – This novel agricultural lifestyle initially depressed adaptation and health, leading to intense natural selection for adaptations to the digestion of foods derived from grasses and milk, which has since produced adaptation to agricultural conditions at early ages. … Continue reading

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Thesis 49

Thesis #49 – In agricultural populations over the last ten thousand years, the longer-sustained effectiveness of natural selection has resulted in an age-dependent pattern of falling adaptation to agricultural conditions in which functional decline is sustained over a longer period … Continue reading

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