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- Rose offers the scientific context/framework for Ancestral Health
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- What foods did we evolve to eat?
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- So when will you lose your health – Part 5 – What to do
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- So when will you lose your health? – Part 3 – When you don’t know this
- So when will you lose your health – Part 2 – When you live in the wrong environment
- So when will you lose your Health? Part 1 – The Healthspan
- The Great Return – Part 5 – Why Food is the way home
- Michael Rose – Saved my life
- Bill Maher Speaks the Truth about Health
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- Why did we stray so far from our Evolutionary Best Fit?
- The Great Return – Part 3 – The Rules of the New World#2 – A Vision
- The Great Return – Part 2 – The “Industrial Clearances” and what they mean to us
- The Great Return Part 1 – Getting back our right relationship with Nature – A series
- Why are we so fat in rural areas – Part 4 – We don’t fit the culture
- Why are we so fat in rural settings? – Part 3 – Our Ancestry!
- Why are people in rural setting fat – Part 2 – Because our friends are – It’s Social!
- Why are rural folks fatter than urban – It’s not laziness it is environment – Part 1
- Trust – Part of our Biology – Dr Jonathan Shay
- Your Mind and your Health – Part 4 – Why the Tribe – Community – is the best Environment to help us
- Your mind and your health – Part 3 – How do we change deep rooted thoughts/habits?
- Your Mind and your Health – Part 2 – The Power of Neuroplasticity
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- Your Mind & Your Health – Part 1 – Overcoming bad environments
- How do you get control and power – Riot or take it for yourself?
- Crohns Disease – Typical Bad Advice you get
- Your Baby – Bathtime – What is safe? – Novel Environments
- Diet – What you need to know based on your heritage
- Diet – Where your ancestral heritage is important
- Are you at risk of getting ill? Yes when we get older
- Aging – What is it and why you can avoid it’s ravages
- Where can we find answers to the questions raised by Michael Rose? A Hack Community
- The PaleoGraphic – The Story in Pictures
- Michael’s Recent Interview
- Talking about Environments – carbs are novel
- Talking about environments – What’s in your shampoo, soap, deodorant and face cream?
- Talking about Environments – What about your mouth?
- As primates we need to live in the “right” social environment – much of our illness stems from a poor fit – the cure is a better fit.
- Michael’s Rose’s “Twin Sister?” – Dr Mary Vernon – The practical aspect of the 55 Theses
- The “Plateau” – Thesis #30 in action
- The most important social environment to get right – the family
- We need the best fit to our ideal social status as well as to our ideal diet
- Sir Michael Marmot to expand the Whitehall Study to look at why we “age” differently
- Cancer is not a disease but a part of mammalian life – Paul Davies
- Welcome to Michael Rose’s 55 Theses – A New Context for Health
- The Scientific Challenge
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Category Archives: Forces of Natural Selection
Rose offers the scientific context/framework for Ancestral Health
Science is a mess today as is medicine. Every day we hear a new this or that. Many hold very strong beliefs based on what? What was missing was a context for health. This is what Michael has offered us. … Continue reading
Posted in "Paleo", A New Vision, Ancestry, Context, Diet, Forces of Natural Selection, The New Science, Theses
Tagged Rob Wolff
1 Comment
Ancestry Foundation – A great centre of information – Videos from the conference
Earlier this month, the Ancestry Foundation hosted the first of what will be many conferences on Health as seen through the perspective of Evolution. Here is the link to the many excellent videos Here is the link to the slides and here … Continue reading
Posted in "Paleo", A New Vision, Ancestry, Context, Diet, Environments, Forces of Natural Selection, Physiology, Resources, The New Science
Tagged Ancestry Foundation
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So when will you lose your health – Part 2 – When you live in the wrong environment
You get ill when you look like this – this is how I looked aged 59 – I weighed 205 lbs. How I look here has all the signs that you have not lived your life according to the rules. … Continue reading
The Great Return – Part 5 – Why Food is the way home
I have been trying to see how #Paleo is more than a diet. Taking control of our health will in the end be about changing how we live. For our system today not only restricts our diet to shit but … Continue reading
Posted in "Paleo", A New Vision, Context, Environments, Forces of Natural Selection, Population
Tagged Food, Health, Systems
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Diet – Where your ancestral heritage is important
Surely we must have adapted to agriculture by now? The answer is no and sort of yes to that question. It depends on what your ancestral heritage is or how long you have been exposed to agriculture. Let’s take dairy. … Continue reading
Are you at risk of getting ill? Yes when we get older
My son who is 31 likes what he sees in how I have changed but is having trouble with giving up modern foods for himself. Especially beer! I told him that, as a Scot – he is a Celt and … Continue reading
Posted in Aging, Ancestry, Diet, Environments, Forces of Natural Selection, Plateau, Population
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Michael’s Recent Interview
Michael is interviewed by Jimmie Moore on how Evolution plays such a role and also on how diet is so important. Here MR summarizes the key factors of the 55 in a few minutes.
Posted in "Paleo", A New Vision, Aging, Ancestry, Context, Diet, Environments, Evolutionary Novelty, Forces of Natural Selection, Physiology, Plateau, Population, The New Science, The Science
Tagged Jimmie Moore, LLVLC Show
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The “Plateau” – Thesis #30 in action
Here is a short video of Ruth – soon to be 100. My real point of posting her video is to remind us all that there is a plateau waiting for us as we get older. If we are not … Continue reading
Thesis 21
Thesis #21 – Multiple pharmaceutical substances or nutritional supplements will only ameliorate aging to the extent that they achieve genome-wide tuning similar to that which natural selection achieves when its forces are strengthened at later ages. So how best to … Continue reading
Posted in Forces of Natural Selection, Theses
Tagged Michael Rose, Michael Rose 55 Theses
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Thesis 24
Thesis #24 – Altering all cell-molecular regulatory signaling during the aging phase will provide at most partial amelioration for the problem of declining adaptation, because dysfunctional signaling will also arise at organ and systemic levels as a result of the … Continue reading
Posted in Complexity, Context, Forces of Natural Selection, Theses, Tuning
Tagged Michael Rose, Michael Rose 55 Theses
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Thesis 27
Thesis #27 – Among populations which have had their forces of natural selection strengthened experimentally, detectable improvements in adult survival and reproduction have been observably achieved within dozens of generations. So there I am, in 1977, realizing that all evolution … Continue reading
Posted in A New Vision, Aging, Forces of Natural Selection, The New Science, Theses
Tagged Hamilton, Michael Rose, Michael Rose 55 Theses
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Thesis 28
Thesis #28 – Among such experimental populations evolving greater levels of adaptation at later adult ages, evolutionary changes in (a) structural gene frequency, (b) gene regulation, (c) patterns of cumulative damage, and (d) still other features of physiological function will … Continue reading
Posted in A New Vision, Aging, Context, Forces of Natural Selection, The New Science, Theses
Tagged Michael Rose, Michael Rose 55 Theses
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Thesis 29
Thesis #29 – Species with fully symmetrical fission as the sole means of reproduction do not have a declining force of natural selection acting on survival, and they do not evolve aging phases in which all individuals show declining survival. … Continue reading
Posted in A New Vision, Aging, Complexity, Constraints, Forces of Natural Selection, Reproduction, The New Science, Theses
Tagged Michael Rose, Michael Rose 55 Theses
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Thesis 30
Thesis #30 – The forces of natural selection plateau at zero values at very late adult ages, and do not decline further for all subsequent ages. This is the most important thing of all, even if no one understood what … Continue reading
Posted in A New Vision, Aging, Forces of Natural Selection, Physiology, The New Science, Tuning
Tagged Michael Rose, Michael Rose 55 Theses
1 Comment
Thesis 31
Thesis #31 – After the forces of natural selection plateau, it is possible for survival and reproduction to plateau at positive values due to age-independent beneficial effects of some genetic variants. As with modern physics, again, it is often difficult … Continue reading
Posted in A New Vision, Aging, Complexity, Context, Forces of Natural Selection, The New Science, The Plateau, Tuning
Tagged Charlesworth, Hamilton, Michael Rose, Michael Rose 55 Theses
1 Comment
Thesis 32
Thesis #32 – Before the forces of natural selection plateau, it is possible for genetic drift, due to small population sizes among other possibilities, to weaken the ability of natural selection to distinguish among genetic variants affecting later adult life, … Continue reading
Posted in A New Vision, Aging, Constraints, Forces of Natural Selection, Population, Reproduction, The New Science, The Plateau
Tagged Mueller
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Thesis 33
Thesis #33 – When late-adult plateaus in survival and reproduction occur, members of biological cohorts that reach such plateaus will show stabilization of some but not necessarily all functional characters. Evolutionary theory makes a simple prediction about how the key … Continue reading
Posted in Aging, Complexity, Forces of Natural Selection, Physiology, Population, Reproduction, The New Science, The Plateau, Theses
Tagged Shahrestani
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Thesis 34
Thesis #35 – Severe antagonistic pleiotropy can cause the evolution of zero late-adult survival probability even under ideal conditions, when genetic trade-offs between early reproduction and subsequent adult survival are sufficiently strong. Not all organisms have three phases to their … Continue reading
Posted in A New Vision, Aging, Constraints, Forces of Natural Selection, Physiology, Reproduction, The New Science, Theses, Trade Offs, Tuning
Tagged Michael Rose, Michael Rose 55 Theses
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Thesis 35
Thesis #35 – The ages at which the forces of natural selection plateau depend on the last ages of reproduction and survival in the evolutionary history of a population, allowing experimental evolution of the cessation of aging by deliberately changing … Continue reading
Posted in A New Vision, Aging, Forces of Natural Selection, Population, Reproduction, The New Science, The Plateau, Theses
Tagged Michael Rose, Michael Rose 55 Theses, Mueller
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Thesis 36
Thesis #36 – Experimental populations which have evolved different time-points for the cessation of aging can be used to uncover the biological foundations that determine the timing of the cessation of aging. During the 1980s and 1990s, my laboratory devoted … Continue reading
Posted in A New Vision, Aging, Forces of Natural Selection, Physiology, The New Science, The Science, Theses
Tagged Burke, Michael Rose, Michael Rose 55 Theses, Shahrestani
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Thesis 37
Thesis #37 – Patterns of aging, including the rates of decline of functional characters and the timing of any cessation in such decline, depend on the environments in which cohorts are raised and live as adults. (Picture of Einstein talking … Continue reading
Posted in A New Vision, Aging, Constraints, Environments, Forces of Natural Selection, The New Science, The Plateau, The Science, Theses
Tagged Leo Szilard, Santos
1 Comment
Thesis 39
Thesis #39 – Patterns of adaptation are jointly determined by long-antecedent evolutionary patterns of natural selection, mutation, and inbreeding, as well as the immediate impact of environmental manipulation. In studying the aging phase and other patterns of adaptation in an … Continue reading
Posted in A New Vision, Aging, Constraints, Environments, Forces of Natural Selection, Population, The New Science, Theses
Tagged Michael Rose, Michael Rose 55 Theses
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Thesis 40
Thesis #40 – Experimental strategies for the study of aging that involve the introduction of novel mutations or increased levels of inbreeding will systematically impair the scientific study of aging, as they degrade and disrupt adaptation generally. At this point, … Continue reading
Posted in A New Vision, Aging, Constraints, Context, Forces of Natural Selection, The Science, Theses
Tagged Michael Rose, Michael Rose 55 Theses
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Thesis 41
Thesis #41 – Experimental strategies for the study of aging that involve the use of environments that are evolutionarily novel will systematically impair the scientific study of aging, as natural selection will not have previously fostered adaptation to such novel … Continue reading
Posted in A New Vision, Aging, Complexity, Constraints, Context, Environments, Evolutionary Novelty, Forces of Natural Selection, Physiology, The New Science, The Science, Theses
Tagged Hamilton, Michael Rose, Michael Rose 55 Theses
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Thesis 42
Thesis #42 – As a pattern of age-dependent adaptation, aging and the post-aging period are best studied using the range of methods used to study adaptation by evolutionary biologists, such as the comparative method, experimental evolution, and genomics. By this … Continue reading
Posted in A New Vision, Aging, Context, Forces of Natural Selection, The New Science, The Science, Theses
Tagged Charlesworth, Finch, Hamilton, Martin, Michael Rose, Michael Rose 55 Theses
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Thesis 43
Thesis #43 – Experimental manipulation of the forces of natural selection is one of the most powerful methods of studying the biological foundations of aging, because it can direct experimental evolution to produce extensive genetic differentiation with respect to both … Continue reading
Posted in A New Vision, Aging, Context, Experimental Evolution, Forces of Natural Selection
Tagged Hamilton, Michael Rose, Michael Rose 55 Theses
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Thesis 44
Thesis #44 – Most of our ancestral hominin populations of the last million years benefited from increased forces of natural selection at early adult ages under conditions of relatively abundant nutrition derived from hunting, gathering, and cooking and an increased … Continue reading
Posted in A New Vision, Context, Environments, Forces of Natural Selection, Population, The New Science, The Science, Theses
Tagged Michael Rose, Michael Rose 55 Theses
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Thesis 45
Thesis #45 – Our ancestral hunter-gatherer populations had generally low population densities, and thus low effective population sizes, which produced relatively early cessation of aging at relatively high function due to genetic drift. With very low population densities among our … Continue reading
Posted in A New Vision, Aging, Context, Environments, Forces of Natural Selection, Population, Reproduction, The New Science, The Plateau, The Science, Theses, Trade Offs, Tuning
Tagged Food and Western Disease, Lindeberg, Michael Rose, Michael Rose 55 Theses
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Thesis 46
Thesis #46 – In the last ten to twenty thousand years, some human populations adopted extensive agricultural cultivation of grass species and the use of milk from other mammals for nutrition, a novel environment which changed the action of natural … Continue reading
Posted in A New Vision, Aging, Context, Environments, Evolutionary Novelty, Forces of Natural Selection, Population, The New Science, The Plateau, The Science, Theses
Tagged Michael Rose, Michael Rose 55 Theses
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Thesis 47
Thesis #47 – This novel agricultural lifestyle initially depressed adaptation and health, leading to intense natural selection for adaptations to the digestion of foods derived from grasses and milk, which has since produced adaptation to agricultural conditions at early ages. … Continue reading
Michael Rose's 55 