Category Archives: Forces of Natural Selection

The “Plateau” – Thesis #30 in action

Here is a short video of Ruth – soon to be 100. My real point of posting her video is to remind us all that there is a plateau waiting for us as we get older. If we are not … Continue reading

Posted in Aging, Forces of Natural Selection, Plateau | Tagged | 2 Comments

Thesis 21

Thesis #21 – Multiple pharmaceutical substances or nutritional supplements will only ameliorate aging to the extent that they achieve genome-wide tuning similar to that which natural selection achieves when its forces are strengthened at later ages. So how best to … Continue reading

Posted in Forces of Natural Selection, Theses | Tagged ,

Thesis 24

Thesis #24 – Altering all cell-molecular regulatory signaling during the aging phase will provide at most partial amelioration for the problem of declining adaptation, because dysfunctional signaling will also arise at organ and systemic levels as a result of the … Continue reading

Posted in Complexity, Context, Forces of Natural Selection, Theses, Tuning | Tagged ,

Thesis 27

Thesis #27 – Among populations which have had their forces of natural selection strengthened experimentally, detectable improvements in adult survival and reproduction have been observably achieved within dozens of generations. So there I am, in 1977, realizing that all evolution … Continue reading

Posted in A New Vision, Aging, Forces of Natural Selection, The New Science, Theses | Tagged , ,

Thesis 28

Thesis #28 – Among such experimental populations evolving greater levels of adaptation at later adult ages, evolutionary changes in (a) structural gene frequency, (b) gene regulation, (c) patterns of cumulative damage, and (d) still other features of physiological function will … Continue reading

Posted in A New Vision, Aging, Context, Forces of Natural Selection, The New Science, Theses | Tagged ,

Thesis 29

Thesis #29 – Species with fully symmetrical fission as the sole means of reproduction do not have a declining force of natural selection acting on survival, and they do not evolve aging phases in which all individuals show declining survival. … Continue reading

Posted in A New Vision, Aging, Complexity, Constraints, Forces of Natural Selection, Reproduction, The New Science, Theses | Tagged ,

Thesis 30

Thesis #30 – The forces of natural selection plateau at zero values at very late adult ages, and do not decline further for all subsequent ages. This is the most important thing of all, even if no one understood what … Continue reading

Posted in A New Vision, Aging, Forces of Natural Selection, Physiology, The New Science, Tuning | Tagged , | 1 Comment