Tag Archives: Michael Rose 55 Theses

Thesis #6

Thesis #6 Natural selection produces good health only when new deleterious mutations are rare or small in magnitude; very few novel mutations will have large and generally beneficial effects, in an environment to which a population is well-adapted. Mutation is … Continue reading

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Thesis #8

Thesis #8 This complex genomic foundation for adaptation in turn produces a still more complex network of interacting molecules that sustain survival, health, fertility, and function. Arising from the genetic complexity of healthy function is a still more complex set … Continue reading

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Thesis #9

Thesis #9 The forces of natural selection weaken with adult age in species that have distinguishable adults and no fissile reproduction. We now face the prospect of developing a 21st Century biology based on formal, mathematical, and computational tools.  It … Continue reading

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Thesis #10

Thesis #10 When the forces of natural selection weaken with adult age, declining survival and fertility evolve in adulthood, and thus produce the decline in health which is commonly called ‘aging.’ In animals like mammals and insects, the Force of … Continue reading

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Thesis 12

Thesis #12 – Aging is a pattern of declining or de-tuned adaptation that is correlated with adult age only because adult age is at first strongly correlated with declining forces of natural selection. We have all seen sunrise and sunset.  … Continue reading

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Thesis 13

Thesis #13 – The declining forces of natural selection lead to an evolutionary failure to establish the genomic information required for tuning the complex networks of life well enough to provide a high level of health indefinitely; there is no … Continue reading

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Thesis 14

Thesis # 14 – Aging hypotheses based solely on supposed universal imperfections of molecular, cell, or organismal physiology are wholly falsified by the existence of biological species that do not exhibit falling average rates of survival and reproduction among large cohorts … Continue reading

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