Tag Archives: Michael Rose 55 Theses

Thesis 42

Thesis #42 – As a pattern of age-dependent adaptation, aging and the post-aging period are best studied using the range of methods used to study adaptation by evolutionary biologists, such as the comparative method, experimental evolution, and genomics. By this … Continue reading

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Thesis 43

Thesis #43 – Experimental manipulation of the forces of natural selection is one of the most powerful methods of studying the biological foundations of aging, because it can direct experimental evolution to produce extensive genetic differentiation with respect to both … Continue reading

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Thesis 44

Thesis #44 – Most of our ancestral hominin populations of the last million years benefited from increased forces of natural selection at early adult ages under conditions of relatively abundant nutrition derived from hunting, gathering, and cooking and an increased … Continue reading

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Thesis 45

Thesis #45 – Our ancestral hunter-gatherer populations had generally low population densities, and thus low effective population sizes, which produced relatively early cessation of aging at relatively high function due to genetic drift. With very low population densities among our … Continue reading

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Thesis 46

Thesis #46 – In the last ten to twenty thousand years, some human populations adopted extensive agricultural cultivation of grass species and the use of milk from other mammals for nutrition, a novel environment which changed the action of natural … Continue reading

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Thesis 48

Thesis #48 – Agricultural populations have also undergone substantial increases in population size compared to those of their ancestral hunter-gatherer populations, which increased the effectiveness of natural selection at later adult ages, resulting in the evolution of a delay in … Continue reading

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Thesis 49

Thesis #49 – In agricultural populations over the last ten thousand years, the longer-sustained effectiveness of natural selection has resulted in an age-dependent pattern of falling adaptation to agricultural conditions in which functional decline is sustained over a longer period … Continue reading

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Thesis 50

Thesis #50 – Children and young adults with predominantly agricultural ancestry are well adapted to agricultural conditions of nutrition and activity, but children and young adults without agricultural ancestry are not adapted to such conditions. Let us address with particular … Continue reading

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Thesis 51

Thesis #51 – Older adults from all human populations are not adequately adapted to agricultural patterns of nutrition and activity, resulting in an amplification of aging under such conditions. Naturally, older adults from non-agricultural populations will be no better adapted … Continue reading

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Thesis 53

Thesis #53 – Young people with significant agricultural ancestry can sustain their health with agricultural patterns of nutrition and activity, but not with an evolutionarily novel industrial lifestyle. It is tempting to suppose that young people with agricultural ancestry are … Continue reading

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Thesis 55

Thesis #55 – Once this switch to a hunter-gatherer lifestyle among older adults has become widespread, further changes that would enhance human health at later ages can be discovered using evolutionary research tools, such as experimental evolution with model organisms … Continue reading

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